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Photonics Inc
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Verasonics Inc
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Keysight Technologies
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Photonics Inc
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Anritsu Co Ltd
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Electro-Optical Systems Inc
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Journal: Scientific Reports
Article Title: Dynamic mode decomposition based Doppler monitoring of de novo cavitation induced by pulsed HIFU: an in vivo feasibility study
doi: 10.1038/s41598-024-73787-w
Figure Lengend Snippet: Illustration of the experimental setup for pHIFU exposures of surgically exposed porcine liver in vivo and the ultrasound imaging sequences for treatment guidance. (a) A HIFU transducer equipped with water-filled coupling cone on the front and a coaxial imaging probe mounted at the center opening were used to deliver pHIFU pulses and acquire imaging data, respectively. A midline abdominal incision was made, allowing the cone tip to be in direct contact with the liver surface. (b) The ultrasound imaging sequence. 13 planewave Doppler pulses were emitted immediately after each pHIFU pulse, followed by conventional ray-line B-mode imaging pulses. The imaging probe was operated in ‘listening mode’ for passive cavitation detection (PCD), capturing radio-frequency (RF) signals during HIFU pulses to monitor inertial cavitation activity.
Article Snippet: The processing was applied to the 2-dimensional in-phase quadrature (I/Q) modulated
Techniques: In Vivo, Imaging, Sequencing, Activity Assay
Journal: Scientific Reports
Article Title: Dynamic mode decomposition based Doppler monitoring of de novo cavitation induced by pulsed HIFU: an in vivo feasibility study
doi: 10.1038/s41598-024-73787-w
Figure Lengend Snippet: Illustration of the principle of DMD processing of planewave Doppler data. I/Q modulated planewave images underwent DMD processing, yielding a reduced order set of spatiotemporal modes along with modal parameters such as mode frequency and temporal decay rate. From these unclassified modes, bubble modes were identified using k-means clustering and a contrast-based thresholding method. These bubble modes were then reconstructed into bubble images, which were further processed using a conventional Doppler power algorithm. Finally, the Doppler power maps corresponding to each pHIFU pulse were cumulatively summed over all pHIFU pulses, enabling a comparison with histological images.
Article Snippet: The processing was applied to the 2-dimensional in-phase quadrature (I/Q) modulated
Techniques: Comparison